diff --git a/Resources/Locale/en-US/species/slime.ftl b/Resources/Locale/en-US/species/slime.ftl
new file mode 100644
index 0000000000..87b77511ba
--- /dev/null
+++ b/Resources/Locale/en-US/species/slime.ftl
@@ -0,0 +1 @@
+slime-hurt-by-water-popup = The water melts some of your slime away!
diff --git a/Resources/Prototypes/Damage/modifier_sets.yml b/Resources/Prototypes/Damage/modifier_sets.yml
index ae68d48f48..f3b10b32f2 100644
--- a/Resources/Prototypes/Damage/modifier_sets.yml
+++ b/Resources/Prototypes/Damage/modifier_sets.yml
@@ -62,3 +62,13 @@
     Heat: 2.0
   flatReductions:
     Blunt: 5
+
+- type: damageModifierSet
+  id: Slime
+  coefficients:
+    Blunt: 0.6
+    Slash: 1.2
+    Piercing: 1.2
+    Cold: 1.5
+    Poison: 0.8
+
diff --git a/Resources/Prototypes/Entities/Mobs/Species/slime.yml b/Resources/Prototypes/Entities/Mobs/Species/slime.yml
index 4df250cf48..58666b2515 100644
--- a/Resources/Prototypes/Entities/Mobs/Species/slime.yml
+++ b/Resources/Prototypes/Entities/Mobs/Species/slime.yml
@@ -96,6 +96,34 @@
     - type: HumanoidAppearance
       hairMatchesSkin: true
       hairAlpha: 0.5
+    - type: Damageable
+      damageContainer: Biological
+      damageModifierSet: Slime
+    - type: Barotrauma
+      damage:
+        types:
+          Blunt: 1.4 #per second, scales with pressure and other constants. Twice as much as humans.
+    - type: Reactive
+      groups:
+        Flammable: [ Touch ]
+        Extinguish: [ Touch ]
+      reactions:
+      - reagents: [ Water, SpaceCleaner ]
+        methods: [ Touch ]
+        effects:
+        - !type:WashCreamPieReaction
+      - reagents: [ Water ]
+        methods: [ Touch ]
+        effects:
+        - !type:HealthChange
+          scaled: true
+          damage:
+            types:
+              Heat: 2
+        - !type:PopupMessage
+          type: Local
+          messages: [ "slime-hurt-by-water-popup" ]
+          probability: 0.25
     - type: Butcherable
       meat: FoodMeatSlime